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KMID : 1007519990080040251
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Food Science and Biotechnology
1999 Volume.8 No. 4 p.251 ~ p.256
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Screening for Plants to Suppress Oxidation of Pulmonary Microsome Exposed to Cigarette Smoke
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Kim, Sang Hee
Kim, Seok Joong/Han, Dae Seok
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Abstract
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The abilities of natural antioxidants and edible plants to protect lung from cigarette smoke were evaluated using the gas phase cigarette smoke and the pulmonary microsome. When the gas phase smoke prepared under standard puffing condition was supplied to the pulmonary microsome of rats, lipid peroxidation (LPO) of microsome expressed as the quantity of thiobarbituric acid reactive substance (TBARS) was increased with the number of cigarettes. When natural products were added to microsome prior to supplying smoke, most of the 12 natural antioxidants tested showed high protection at 10 mM concentration, and ascorbic acid, especially, had the highest effect of 94% followed by catechin (69%) and caffeic acid (56%). Among the aqueous extracts of 65 edible plants, apple, pumpkin (overgrown), Chinese quince, and peach (yellow} inhibited LPO by more than 30%, and the effects of green tea, leek, pear, shiitake, dropwort, Ganoderma lucidum, and chestnut were above 20%.
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KEYWORD
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